Central London Intestinal Failure Partnership
The Central London Intestinal Failure Partnership (CLIP) is a collaboration between Barts Health, Guy's and St Thomas', and University College London Hospitals. We are three of the largest NHS trusts in the country serving a patient population of over 5 million people, working together with over 15 hospitals across London.
The purpose of the CLIP is to facilitate the provision of the best care and experience for all intestinal failure patients within North Central, East, and South East London.
What is Intestinal Failure?
Intestinal failure is defined as the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth.
The reduction of gut absorptive function that doesn't require any intravenous supplementation to maintain health and/or growth, can be considered as “intestinal insufficiency” (or deficiency).
Functional classification
On the basis of onset, metabolic, and expected outcome criteria, IF is classified as:
Type I acute, short-term, and often self-limiting condition
Type II prolonged acute condition, often in metabolically unstable patients, requiring complex multi-disciplinary care and intravenous supplementation over periods of weeks or months
Type III chronic condition, in metabolically stable patients, requiring intravenous supplementation over months or years. It may be reversible or irreversible.
Pathophysiological classification
IF can be classified into five major pathophysiological conditions, which may originate from various gastrointestinal or systemic diseases:
Short bowel
Intestinal fistula
Intestinal dysmotility
Mechanical obstruction
Extensive small bowel mucosal disease
OUR NETWORK
